Course Content
TRANSPORT IN PLANTS AND ANIMALS
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EXCRETION AND HOMEOSTASIS
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Biology Form 2
About Lesson

Blood Clotting Mechanisms

When blood flows from a wound the platelets rupture on exposure to air releasing an enzyme called thrombokinase (thromboplastin).

This enzyme converts prothrombin to an active enzyme thrombin in the presence of Calcium ion.

It also neutralizes an anti- coagulant factor (heparin) which is naturally found in blood.

Prothrombin is formed in the liver in the presence of vitamin K.

Thrombin then converts the soluble plasma protein fibrinogen into insoluble fibrin which forms a meshwork of fibres on the cut surface trapping blood cells to form a clot. The clot prevents further bleeding.

Importance of blood clotting

  • It prevents excessive loss of blood from the blood tissues
  • Prevents entry of pathogens into the body through wounds.
  • It initiates the wound-healing process.
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